ABSTRACT
Background: We were conducted this study to assess the prevalence of food insecurity in heart failure patients households and the relationship between food security and some variables in this households
Methods: In this cross sectional study, a total of 300 heart failure patients' households were studied in Imam Reza hospital of Mashhad. The Iranian version of household food insecurity access scale was used to measure food security
Results: Among the participants in this study, 129 patients [43%] were secure, 42 patients [14%], 82 patients [27.3%] and 47 patients [15.7%] were mild, moderate and sever insecure, respectively. Chi-square test results show that there is a strong association between diabetes, hypertension, body mass index [BMI], and food security distribution [P < 0.01]
Conclusions: Based on our findings, food insecurity is mild to severe prevalent in heart failure patients households, meanwhile there is a strong relationship between diabetes, hypertension, BMI and food security status, so it is important to assess their food status and prevent from worsening their nutritional status
ABSTRACT
Background: In acute lymphoblastic leukemia [ALL] the bone marrow loses its ability in the differentiation and maturation of blood cells at different stages. Zinc and copper are important co-factors for several enzymes and play an important role in maintenance of DNA integrity. Changes in serum levels of zinc and copper have been found in lymphoproliferative disorders. In the present study, the aim was to compare serum levels of zinc, copper, vitamin D, and inflammatory markers after eight courses of chemotherapy
Methods: Participants of this study included 30 ALL patients in the age range of 15 to 65 years. A 10 mL blood sample was taken before and after eight courses of chemotherapy. The concentration of Zinc, Copper, hs-CRP, vitamin D and malondialdehyde [MDA] were measured
Results: There was a significant increase in serum zinc [121.7 +/- 18.05 microg/dL before chemotherapy and 156.6 +/- 25.00 microg/dL after chemotherapy] and a significant decrease in serum copper [661.9 +/- 190.1 microg/dL before chemotherapy and 402.2 +/- 93.5 microg/dL after chemotherapy] and a significant decrease in Malondialdehyde and serum vitamin D were observwd. Further, no significant differences were observed in hs-CRP after chemotherapy
Conclusion: Results showed that chemotherapy could decrease the burden of disease by increasing serum zinc and decreasing serum copper
ABSTRACT
Tocotrienols [T3] were neglected in the past; today, get attentions due to their antioxidant and none-antioxidant activity. The objective of this study was to evaluate the effects of the daily intake of 200 mg T3 added in canola oil over 8 weeks on microalbuminuria, inflammation, and nitrosative stress in type 2 diabetic patients. This study was a double-blinded, placebo-controlled, randomized trial. A total of 50 patients with T2DM and FBS >126 mg/dl treated by non-insulin hypoglycemic drugs were randomly assigned to receive either 15 ml T3-enriched canola oil [200 mg/day T3] or pure canola oil for 8 weeks. Urine microalbumin, volume and creatinine levels, serum hs-CRP, and nitric oxide [NO] levels were measured before and after intervention. From 50 patients participated in this study, 44 completed the study. There were no significant differences in baseline characteristics, dietary intake, and physical activity between groups. Urine microalbumin and serum hs-CRP were declined significantly in T3-treated group. At the end of the study, patients who treated with T3 had lower urine microalbumin [11 [9, 25] vs. 22 [15, 39.75] nmol/dl, P = 0.003] and hs CRP changes [-10.91 +/- 15.5 vs. -9.88 +/- 27.5 Pg/ml, P = 0.048] than control group. A non-significant decrease was also observed in serum NO level in T3-treated group with no changes in urine volume and creatinine levels. These findings indicate that T3 leads to ameliorate proteinuria and can protect the kidney against inflammation [hs-CRP] and nitrosative stress [NO]
ABSTRACT
This study was conducted to identify the dietary patterns among workers of Oil Terminals Company and to assess their association with socio-demographic and lifestyle factors. The sample size [392] was estimated by considering minimum correlation [r=0.2] between variables. This cross-sectional study was conducted in a representative sample of workers selected by a stratified random-sampling method [all offices of the company]. The head of company provided a list of workers, and the proportion of each center was specified via ni=ki/N × n [ni=number of participants from each center, ki=number of each center workers, N=number company workers, n= sample size [392]].Dietary pattern was identified by valid food frequency questionnaire containing 168 food items with specific serving size consumed by Iranians. Major dietary patterns analyzed by factor analysis. General characteristics across tertiles were compared by ANOVA and chi-square tests were used where appropriate. In addition, we used multivariate logestic regression tests to assess the relationship between demographic, socioeconomic and lifestyle variables and the adherence to the dietary patterns. Two major dietary patterns were extracted: "Healthy pattern" characterized by high consumption of fruits, fish, yellow vegetables, potato, garlic, whole cereals, yogurt drink, and salt. The second one named "unhealthy pattern" characterized by high consumption of soft drinks, sugar, mayonnaise, sweets, eggs, butter, and processed meat, high- fat dairy products, organ meat, French fries, refined cereals, snacks and artificial juice. Work hours were positively correlated [b=0.14; p<0.01] and being single [b=-0.4, p<0.05] and full time work in comparison with part-time work [b=-0.5, p<0.01] was negatively correlated with healthy dietary pattern, whereas age [b=-0.3, p<0.05], dieting [b=-0.4, p<0.01] and history of hyperlipidemia had negative correlation [b=-0.41, p<0.01] with unhealthy dietary pattern. Our findings show the association between socio-demographic, lifestyle factors and dietary patterns of the workers
ABSTRACT
Type 2 diabetes is the most common metabolic disorder worldwide. Traditional herbs and spices can be used to control blood glucose concentrations. The objective of this study was to evaluate the effects of the daily intake of three grams cinnamon over eight weeks on glycemic status, lipid profiles and body composition in type 2 diabetic patients. A double blind, randomized, placebo controlled clinical trial was conducted on 44 patients with type 2 diabetes. Participants were randomly assigned to take either a three g/day cinnamon supplement [n=22] or a placebo [n=22] for eight weeks. Weight, height, body fat mass and systolic and diastolic blood pressure were measured at baseline and after intervention. The fasting blood glucose, insulin, HbA1c, total cholesterol, LDL C, HDL C, Apo lipoprotein A I and B were measured at baseline and endpoint. From 44 subjects participated in this study 37 completed the study. There were no significant differences in baseline characteristics, dietary intake and physical activity between groups. In the treatment group, the levels of fasting blood glucose, HbA1c, triglyceride, weight, BMI and body fat mass decreased significantly compared to baseline, but not in placebo group. No significant differences were observed in glycemic status indicators, lipid profile and anthropometric indicators between the groups at the end of intervention. These data suggest that cinnamon may have a moderate effect in improving glycemic status indicators